About Nusinersen
Class: | Antisense oligonucleotide
Use: | Treatment of spinal muscular atrophy (SMA) in pediatric and adult patients
Adult dose: | 12 mg (3 mL) administered intrathecally once every 4 months after an initial loading dose of 12 mg (3 mL) on days 0, 14, and 28
Pediatric dose: | 12 mg (3 mL) administered intrathecally once every 4 months after an initial loading dose of 12 mg (3 mL) on days 0, 14, and 28 for patients with SMA
Side effects: | Common side effects include headache, back pain,
Drug Class
Antisense oligonucleotide
Uses & Indications
Treatment of spinal muscular atrophy (SMA) in pediatric and adult patients
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light
Manufacturer & Packaging
Manufacturer: Biogen Idec Inc., U.S.A
Package Size
5ml Vial
Price & Supplier
Price in UAE: AED 463742.00
Dosage Information
Adult Dose
12 mg (3 mL) administered intrathecally once every 4 months after an initial loading dose of 12 mg (3 mL) on days 0, 14, and 28
Pediatric Dose
12 mg (3 mL) administered intrathecally once every 4 months after an initial loading dose of 12 mg (3 mL) on days 0, 14, and 28 for patients with SMA
Side Effects
Common side effects include headache, back pain, nausea, vomiting, constipation, and respiratory infections
Contraindications & Precautions
Hypersensitivity to nusinersen or any component of the formulation; caution in patients with bleeding disorders or those on anticoagulant therapy
Important Warnings
Risk of serious neurological adverse reactions; monitor for signs of infection; potential for thrombocytopenia; ensure proper administration technique to avoid complications such as post-lumbar puncture headache or infection
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.