About Cilastatin Sodium,Imipenem Monohydrate
Class: | Carbapenem antibiotic (combination of Imipenem and Cilastatin)
Use: | Treatment of serious infections caused by susceptible bacteria, including intra-abdominal infections, urinary tract infections, skin and skin structure infections, and pneumonia.
Adult dose: | 500 mg of Imipenem and 500 mg of Cilastatin administered intravenously every 6 to 8 hours, depending on the severity of the infection.
Pediatric dose: | For children over 3 months: 15-25 mg/kg of Imipenem and 15-25 mg/kg o
Drug Class
Carbapenem antibiotic (combination of Imipenem and Cilastatin)
Uses & Indications
Treatment of serious infections caused by susceptible bacteria, including intra-abdominal infections, urinary tract infections, skin and skin structure infections, and pneumonia.
Storage Requirements
Store at room temperature (20-25°C or 68-77°F) in a dry place, protected from light. Reconstituted solutions should be used immediately or stored at 2-8°C for no more than 24 hours.
Manufacturer & Packaging
Manufacturer: Julphar (Gulf Pharmaceutical Industries), U.A.E
Package Size
1 Vial (Powder)
Price & Supplier
Price in UAE: AED 71.00
Dosage Information
Adult Dose
500 mg of Imipenem and 500 mg of Cilastatin administered intravenously every 6 to 8 hours, depending on the severity of the infection.
Pediatric Dose
For children over 3 months: 15-25 mg/kg of Imipenem and 15-25 mg/kg of Cilastatin every 6 to 8 hours, not to exceed 2 g of Imipenem per day.
Side Effects
Common side effects include nausea, vomiting, diarrhea, rash, headache, and phlebitis at the injection site.
Contraindications & Precautions
Hypersensitivity to Imipenem, Cilastatin, or other beta-lactam antibiotics; history of seizures; and severe renal impairment without appropriate dosage adjustment.
Important Warnings
Risk of seizures, particularly in patients with a history of seizures or CNS disorders; potential for Clostridium difficile-associated diarrhea; and caution in patients with renal impairment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.