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Cilastatin Sodium,Imipenem Monohydrate – Uses, Dosage, and Brands in UAE

Brand Name: TIENAM
Strength: 500 mg,500 mg | Form: Powder For Solution For Injection
Price in UAE: AED 70.00
Available in UAE pharmacies

About Cilastatin Sodium,Imipenem Monohydrate

Class: | Carbapenem antibiotic (Imipenem) and dehydropeptidase inhibitor (Cilastatin) Use: | Treatment of serious infections caused by susceptible bacteria, including intra-abdominal infections, urinary tract infections, skin and soft tissue infections, and pneumonia. Adult dose: | 500 mg of Imipenem and 500 mg of Cilastatin administered intravenously every 6 to 8 hours, depending on the severity of the infection. Pediatric dose: | For children over 3 months: 15-25 mg/kg of Imipenem and 15

Drug Class

Carbapenem antibiotic (Imipenem) and dehydropeptidase inhibitor (Cilastatin)

Uses & Indications

Treatment of serious infections caused by susceptible bacteria, including intra-abdominal infections, urinary tract infections, skin and soft tissue infections, and pneumonia.

Storage Requirements

Store at room temperature (20-25°C or 68-77°F) in a dry place. Reconstituted solutions should be used immediately or stored at 2-8°C (36-46°F) for up to 24 hours.

Manufacturer & Packaging

Manufacturer: Merck Sharp & Dohme B.V., NETHERLANDS

Package Size

1 Vial (Dry) + 1 Solvent Ampoule (2ml)

Price & Supplier

Price in UAE: AED 70.00

Dosage Information

Adult Dose

500 mg of Imipenem and 500 mg of Cilastatin administered intravenously every 6 to 8 hours, depending on the severity of the infection.

Pediatric Dose

For children over 3 months: 15-25 mg/kg of Imipenem and 15-25 mg/kg of Cilastatin every 6 to 8 hours, not to exceed 2 g/day.

Side Effects

Nausea, vomiting, diarrhea, rash, headache, and potential for seizures, especially in patients with renal impairment.

Contraindications & Precautions

Known hypersensitivity to Imipenem, Cilastatin, or other beta-lactam antibiotics; history of seizures; and severe renal impairment without appropriate dose adjustment.

Important Warnings

Risk of seizures, particularly in patients with CNS disorders or renal impairment; potential for Clostridium difficile-associated diarrhea; and caution in patients with a history of penicillin allergy.

Other Brands & Strengths Available in UAE

Different brands and strengths of Cilastatin Sodium,Imipenem Monohydrate available in UAE pharmacies:

CILANEM 500 mg,500 mg Powder For Solution For Injection IMIPENEM CILASTATIN 500 mg,500 mg Powder For Solution For Intravenous Injection IMIPENEM CILASTATIN 500 mg,500 mg Powder For Solution For Intravenous Injection IMIPENEM CILASTATIN 500 mg,500 mg Powder For Solution For Intravenous Injection MAXINEM 500 mg,500 mg Powder For Solution For Injection TIENAM 500 mg,500 mg Powder For Solution For Injection TIENAM 500 mg,500 mg Powder For Solution For Intravenous Injection

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

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