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Trastuzumab – Uses, Dosage, and Brands in UAE

Brand Name: HERCEPTIN
Strength: 440 mg | Form: Powder For Solution For Intravenous Injection
Price in UAE: AED 14062.50
Available in UAE pharmacies

About Trastuzumab

Class: | Monoclonal antibody (HER2/neu receptor antagonist) Use: | Treatment of HER2-positive breast cancer (adjuvant and metastatic), gastric cancer, and gastroesophageal junction adenocarcinoma Adult dose: | 8 mg/kg loading dose, followed by 6 mg/kg every 3 weeks for metastatic breast cancer; for adjuvant therapy, 4 mg/kg loading dose, followed by 2 mg/kg weekly for 52 weeks Pediatric dose: | Safety and efficacy not established in pediatric patients; dosing not recommended Side effects

Drug Class

Monoclonal antibody (HER2/neu receptor antagonist)

Uses & Indications

Treatment of HER2-positive breast cancer (adjuvant and metastatic), gastric cancer, and gastroesophageal junction adenocarcinoma

Storage Requirements

Store at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; reconstituted solution should be used immediately or stored at 2°C to 8°C for up to 24 hours

Manufacturer & Packaging

Manufacturer: F. Hoffmann-La Roche Ltd., SWITZERLAND

Package Size

1 Vial (Dry) + 1 Solvent Vial (20ml)

Price & Supplier

Price in UAE: AED 14062.50

Dosage Information

Adult Dose

8 mg/kg loading dose, followed by 6 mg/kg every 3 weeks for metastatic breast cancer; for adjuvant therapy, 4 mg/kg loading dose, followed by 2 mg/kg weekly for 52 weeks

Pediatric Dose

Safety and efficacy not established in pediatric patients; dosing not recommended

Side Effects

Common side effects include fever, chills, nausea, vomiting, diarrhea, headache, fatigue, rash, and infusion-related reactions

Contraindications & Precautions

Known hypersensitivity to trastuzumab or any component of the formulation; caution in patients with a history of heart disease

Important Warnings

Risk of cardiomyopathy and heart failure; monitor cardiac function; potential for infusion reactions; may cause pulmonary toxicity; pregnancy category D (risk to fetus)

Other Brands & Strengths Available in UAE

Different brands and strengths of Trastuzumab available in UAE pharmacies:

CANHERA 150 mg Powder for Concentrate for Solution for Infusion. CANHERA 440 mg Powder For Solution For Intravenous Injection HERCEPTIN 440 mg Powder For Solution For Intravenous Injection HERCEPTIN 600 mg/5ml Solution For Injection KADCYLA 100 mg Powder For Solution For Intravenous Injection KADCYLA 160 mg Powder For Solution For Intravenous Injection

Related Medicines in Same Category

See also: Other Monoclonal antibody (HER2/neu receptor antagonist) medicines available in UAE pharmacies

Pertuzumab Trastuzumab (CANHERA) Trastuzumab (CANHERA) Trastuzumab (HERZUMA) Trastuzumab (HERZUMA) Trastuzumab (OGIVRI) Trastuzumab (TRAZIMERA) Trastuzumab (TRAZIMERA)

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

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