About Calcium Folinate (Leucovorin Calcium)
Class: | Antidote, Chemoprotective agent
Use: | Used to reduce the toxicity of methotrexate, to treat folate deficiency, and as an adjunct in certain cancer therapies (e.g., in combination with fluorouracil for colorectal cancer).
Adult dose: | 15 mg orally once daily for 5 days following high-dose methotrexate therapy; doses may vary based on specific indications and protocols.
Pediatric dose: | 10 mg/m² orally once daily for 5 days following high-dose methotrexate therapy; dosing may var
Drug Class
Antidote, Chemoprotective agent
Uses & Indications
Used to reduce the toxicity of methotrexate, to treat folate deficiency, and as an adjunct in certain cancer therapies (e.g., in combination with fluorouracil for colorectal cancer).
Storage Requirements
Store at room temperature (20-25°C or 68-77°F) in a tightly closed container, protected from light and moisture.
Manufacturer & Packaging
Manufacturer: Hospira Australia Pty Ltd., AUSTRALIA
Package Size
10's
Price & Supplier
Price in UAE: AED 33.35
Dosage Information
Adult Dose
15 mg orally once daily for 5 days following high-dose methotrexate therapy; doses may vary based on specific indications and protocols.
Pediatric Dose
10 mg/m² orally once daily for 5 days following high-dose methotrexate therapy; dosing may vary based on specific clinical situations.
Side Effects
Common side effects include nausea, vomiting, diarrhea, abdominal pain, and allergic reactions (e.g., rash, itching).
Contraindications & Precautions
Hypersensitivity to leucovorin or any component of the formulation; caution in patients with renal impairment.
Important Warnings
Use with caution in patients with a history of hypersensitivity reactions; not a substitute for folic acid in patients with megaloblastic anemia due to vitamin B12 deficiency; monitor for signs of toxicity in patients receiving high-dose methotrexate.
Related Medicines in Same Category
See also: Other Antidote, Chemoprotective agent medicines available in UAE pharmacies
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Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.