About Calcium Folinate (Leucovorin Calcium)
Class: | Antidote, Chemoprotective Agent
Use: | Used to reduce the toxicity of methotrexate, to treat folate deficiency, and as an adjunct in certain cancer therapies (e.g., in combination with fluorouracil).
Adult dose: | 10 mg to 15 mg administered intravenously or intramuscularly every 6 hours for 6 doses, or as directed by a physician based on specific clinical scenarios.
Pediatric dose: | 0.5 mg to 1 mg/kg administered intravenously or intramuscularly every 6 hours for 6 doses, not to
Drug Class
Antidote, Chemoprotective Agent
Uses & Indications
Used to reduce the toxicity of methotrexate, to treat folate deficiency, and as an adjunct in certain cancer therapies (e.g., in combination with fluorouracil).
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from light and do not freeze.
Manufacturer & Packaging
Manufacturer: Vitane Pharma GmbH, GERMANY
Package Size
100ml Glass Vial
Price & Supplier
Price in UAE: AED 433.50
Dosage Information
Adult Dose
10 mg to 15 mg administered intravenously or intramuscularly every 6 hours for 6 doses, or as directed by a physician based on specific clinical scenarios.
Pediatric Dose
0.5 mg to 1 mg/kg administered intravenously or intramuscularly every 6 hours for 6 doses, not to exceed adult dosing; adjust based on clinical condition.
Side Effects
Common side effects include nausea, vomiting, diarrhea, abdominal pain, and allergic reactions (e.g., rash, itching).
Contraindications & Precautions
Hypersensitivity to calcium folinate or any component of the formulation; should not be used in patients with pernicious anemia or other megaloblastic anemias not due to folate deficiency.
Important Warnings
Use with caution in patients with renal impairment; monitor for signs of allergic reactions; not a substitute for folic acid in patients with folate deficiency; ensure proper hydration in patients receiving high-dose methotrexate therapy.
Related Medicines in Same Category
See also: Other Antidote, Chemoprotective Agent medicines available in UAE pharmacies
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Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.